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Test Code ALPRT Alport (Collagen IV Alpha 5 and Alpha 2) Immunofluorescent Stain, Renal Biopsy


Shipping Instructions


1. Advise shipping frozen specimens (unstained slides or tissue block) in Styrofoam transportation coolers filled with dry ice to ensure specimens are received at required specimen stability temperature.

2. Attach the green "Attention Pathology" address label (T498) to the outside of the transport container before putting into the courier mailer.



Necessary Information


A pathology/diagnostic report is required.



Specimen Required


Submit only 1 of the following specimens:

 

Preferred:

Specimen Type: Unstained slides (unfixed)

Source: Kidney tissue or skin tissue

Slides: 1 Slide

Collection Instructions: Submit 1 frozen tissue unstained positively charged glass slide (25- x 75- x 1-mm) per test ordered; sections should be 4-microns thick, centered on the slide, and shipped on dry ice.

 

Acceptable:

Specimen Type: Unfixed tissue block (O.C.T)

Source: Kidney tissue or skin tissue

Specimen Volume: Entire specimen

Collection Instructions:

1. Embed in O.C.T. compound.

2. Freeze specimen and ship on dry ice.

 

Acceptable:

Specimen Type: Wet tissue

Source: Kidney tissue or skin tissue

Supplies: Renal Biopsy Kit (T231)

Container/Tube: Renal Biopsy Kit, Zeus/Michel's

Specimen Volume: Entire specimen

Collection Instructions:

1. Collect specimens according to the instructions in Renal Biopsy Procedure for Handling Tissue for Light Microscopy, Immunofluorescent Histology, and Electron Microscopy.

2. If standard immunoglobulin and complement immunofluorescence has already been performed, ship the residual frozen tissue (must contain glomeruli) on dry ice.


Secondary ID

70593

Useful For

Assisting in the diagnosis of hereditary nephritis (Alport syndrome)

Method Name

Direct Immunofluorescence

Reporting Name

ALPORT Immunofluorescence

Specimen Type

Special

Specimen Stability Information

Specimen Type Temperature Time Special Container
Special Frozen

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability

Reference Values

An interpretive report will be provided.

Day(s) Performed

Monday through Friday

Report Available

1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

88346

LOINC Code Information

Test ID Test Order Name Order LOINC Value
ALPRT ALPORT Immunofluorescence In Process

 

Result ID Test Result Name Result LOINC Value
71285 Interpretation 50595-8
71268 Participated in the Interpretation No LOINC Needed
71269 Report electronically signed by 19139-5
71270 Addendum 35265-8
71271 Gross Description 22634-0
71272 Material Received 81178-6
71619 Disclaimer 62364-5
71848 Case Number 80398-1

Specimen Minimum Volume

See Specimen Required